- Mr. Kitty has undergone a redesign for this episode.
- The ending credits feature the full ending theme and shows pictures of "cat breading", instead of the song being cut off and showing a clip from the episode.
- The dialogue between the presidential candidates are recordings of actual conversations.
- The "Taylor Swifting" meme references a real video meme of dogs scooting across the floor.
- This episode over emphasizes and over exaggerates deaths from re-enacting memes due to the same reaction of deaths from planking.
- The video that Professor Lamont showed the kids was copyrighted 2010, but the styles and video quality was clearly 1980's.
- In this episode, Mr. Kitty angrily hisses at Cartman and at one point scratches him, showing that Mr. Kitty is sick of Cartman abusing him all the time.
- A running gag throughout the episode is that various characters get hit by a GE Genesis train in different paint schemes when standing in the middle of train tracks, or in the most ridiculous locations and circumstances.
References to Popular Culture
- Sunday Night Football - The song Eric Cartman sings at the end is a parody of the Sunday Night Football on NBC theme song.
- Taylor Swift and Faith Hill - Taylor Swift and Faith Hill are popular female country singers.
- Oh Long Johnson... - talking cat - This episode uses footage from the "Oh Long Johnson... - talking cat" YouTube video.
- The Selfish Gene - Professor Lamont was explaining memetics, a concept created by Richard Dawkins in his 1976 book The Selfish Gene.
- The Hunger Games - In the newspaper that the the boys were reading, a review of the film The Hunger Games can be seen.
- 2000 and late - Repeatedly mentioned throughout the episode, 2000 and late is a reference to a line in the Black Eyed Peas song Boom Boom Pow.
- Tom Brady - New England Patriots' quarterback. The seated pose he took on the field after his team lost the 2012 Super Bowl became known as "Bradying". 
- Tim Tebow - Former quarterback for the Denver Broncos and New York Giants. The kneeling pose he would take while praying on the sideline became known as "Tebowing". 
- Arthur "Fonzie" Fonzarelli - Fictional character from the T.V. series Happy Days. His trademark gesture of giving a "Thumbs up" pose and saying "Ayy!" is referred to as a meme from the 1970s known as "Fonzying".
- Raiders of the Lost Ark, the first Indiana Jones movie is spoofed when Professor Lamont is called to gym to talk to those two government-men. It is especially underlined by the sunrays coming through windows, his shoulder-bag and finally when he takes out the antique book with hasps to show some past examples.
- This episode, like "You're Getting Old", is one of the few episodes where Eric Cartman and Kyle Broflovski are seen getting along.
- This is Mr. Kitty's first appearance since "Major Boobage".
- In the book featuring a picture of "Fonzying", Richard Dawkins is quoted in the text as saying: "Fonzying showed a giant leap forward in human intelligence, because it was a simple meme with a complicated subtext". He was previously seen in the season 10 episodes, "Go God Go" and "Go God Go XII".
- After Cartman lectures Mr. Kitty, an extra pair of his feet can be seen as he leaves the room.
- ↑ "Video of NBC Sunday Night Football Featuring Faith Hill".
- ↑ Sunday Night Football on NBC on Wikipedia.
- ↑ Taylor Swift on Wikipedia.
- ↑ Faith Hill on Wikipedia.
- ↑ Oh Long Johnson... - talking cat on YouTube.
- ↑ The Selfish Gene on Wikipedia.
- ↑ The Hunger Games on Wikipedia.
- ↑ Boom Boom Pow on Wikipedia.
- ↑ Tom Brady on Wikipedia
- ↑ Tebowing on Wikipedia
- ↑ Fonzie on Wikipedia