- Matt and Trey made this episode due to their ideas for episodes having been used by The Simpsons already.
- This episode marks the last appearance and death of Ms. Choksondik.
- Many fans believe that Ms. Choksondik really died from actually choking on Mr. Mackey's penis, thus fulfilling the irony of her name and ending her life. It is unknown what happened to Mr. Mackey as he was only seen as Mr. Burns in the episode.
- This is Ms. Crabtree's final appearance until her death in "Cartman's Incredible Gift".
- When Chef sings to the boys after he finds out they killed Ms. Choksondik, the music is reused from the episode "Fat Camp".
- A bottle in the background in the autopsy room is labeled "HITLER."
- The Twilight Zone episode Chef refers to is "The Little People".
- The boys use the lyrics "Hammer Time" from the song "Can't Touch This" by MC Hammer as a warning when somebody is coming while their in the autopsy room. Tweek sings some of the song when he fails to remember the code words.
- Below is a table of prominent South Park characters that are "Simpsonized" compared to "The Simpsons" character they parody. If they don't have an equivalent, they are marked with "None":
|South Park character||Dougie||Ms. Crabtree||Mr. Garrison||Chef||News Anchor||Ms. Choksondik||Mr. Mackey||Stan and Kyle|
|The Simpsons equivalent||Bart||Otto Mann||Smithers||Doctor Hibbert||Kent Brockman||None||Mr. Burns||Martin|
|South Park character||Stephen Stotch (unseen)||Linda Stotch (unseen)||Timmy||Cartman||Tweek||Liane Cartman||Mr. Hat|
|The Simpsons equivalent||Principal Skinner||Mrs. Krabappel||Ralph||Nelson||None||Lunchlady Doris||Groundskeeper Willie|
- Tweek is afraid to put the nose on the snowman for fear that it'll come to life and kill him. Stan says, "When has that ever happened...except for that one time?" This is a reference to The Spirit of Christmas: Jesus vs. Frosty.
- Stan mentions the Goldfish he got from his aunt Flo in "Spookyfish".
- Ms. Choksondik's first name is revealed to be Diane.
- Cartman correctly pronounces authority instead of saying it like "authorit-ah". He also does this during the song "Minorities at my Water Park" in the episode "Pee".